BokuBiotech

The Network on Ageing (Netzwerk Altern) is coordinated and implemented by ÖPIA.

Informationen zur Organisation

Institut/Abteilung

Institut für Medizinische Genetik

Organisation

Medizinische Universität Wien

Leiter/in der Forschungseinheit

Univ.-Prof. Mag. Dr. Markus Hengstschläger

Disziplin

Biologie (106)

THEMA Biogerontologie, Geriatrie und Demenzforschung

Bundesland

Wien

Kontakt

Währinger Straße 10

1090

Wien

Telefon (allg.)

+43 1 40160 - 56558

Kontaktperson

DI Dr. Markus Schosserer

E-Mail

markus.schosserer@meduniwien.ac.at

E-Mail (allg.)

markus.schosserer@meduniwien.ac.at

Homepage

https://pbg.meduniwien.ac.at/forschung/forschung-…

Laufende Projekte

CD-Labor für Multimodales Analytisches Imaging von Alterung und Seneszenz der Haut (SKINMAGINE)

Abgeschlossene Projekte

Nsun5 - Einfluss auf Ribosomen und Lebensspanne von Mäusen

Der Fadenwurm Caenorhabditis elegans als einfaches und kostengünstiges Testmodell der menschlichen Gesundheitsspanne

CD-Labor für Biotechnologie der Hautalterung

Die Rolle von spezialisierten Ribosomen in der Zellalterung und Stressabwehr

Publikationen

Wagner, A., Schosserer, M.

2022

, The epitranscriptome in ageing and stress resistance: A systematic review ,

Ageing Research Reviews, Volume 81

DOI: 10.1016/j.arr.2022.101700

Narzt, M.S., Pils, V., Kremslehner, C., Nagelreiter, I.M., Schosserer, M.,..., Grillari, J., Gruber, F., Lämmermann, I.

2020

, Epilipidomics of senescent dermal fibroblasts identify lysophosphatidylcholines as pleiotropic SASP factors ,

Journal of Investigative Dermatology

DOI: 10.1016/j.jid.2020.11.020

Cavinato, M., Madreiter-Sokolowski, C.T., Büttner, S., Schosserer, M., Zwerschke, W., Wedel, S., Grillari, J., Graier, W.F., Jansen-Dürr, P.

2020

, Targeting cellular senescence based on inter-organelle communication, multi-level proteostasis and metabolic control ,

The FEBS Journal

DOI: 10.1111/febs.15631

Weinmüllner, R., Zbiral, B., Becirovic, A., Stelzer, E.M., Nagelreiter, N., Schosserer, M., Lämmermann, I., Liendl, L., Lang, M., Terlecki-Zaniewicz, L., Andriotis, O., Mildner, M., et.al.

2020

, Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging ,

npj Aging and Mechanisms of Disease volume 6, Article number: 4 (2020)

10.1038/s41514-020-0042-x

Heissenberger, C., Rollins, J.A., Krammer, T.L., Nagelreiter, F., Stocker, I., Wacheul, L., Shpylovyi, A., Tav, K., Snow, S., Grillari, J., Rogers, A.N., Lafontaine, D.L.J., Schosserer, M.

2020

, The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans ,

eLife 2020;9:e56205

DOI: 10.7554/eLife.56205

Schosserer, M; Banks, G; Dogan, S; Dungel, P; Fernandes, A; Marolt Presen, D; Matheu, A; Osuchowski, M; Potter, P; Sanfeliu, C; Tuna, BG; Varela-Nieto, I; Bellantuono, I

2019

, Modelling physical resilience in ageing mice ,

Mech Ageing Dev. 2019; 177:91-102

10.1016/j.mad.2018.10.001

Lindl, L; Grillari, J; Schosserer, M

2019

, Raman fingerprints as promising markers of cellular senescence and aging ,

GeroScience

10.1007/s11357-019-00053-7

Terlecki-Zaniewicz, L; Lämmermann, I; Latreille, J; Bobbili, MR; Pils, V; Schosserer, M; Weinmüllner, R; Dellago, H; Skalicky, S; Pum, D; Almaraz, JCH; Scheideler, M; Morizot, F; Hackl, M; Gruber, F; Grillari, J

2018

, Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype ,

Aging (Albany NY). 2018; 10(5):1103-1132

10.18632/aging.101452

Cardoso, AL; Fernandes, A; Aguilar-Pimentel, JA; de Angelis, MH; Guedes, JR; Brito, MA; Ortolano, S; Pani, G; Athanasopoulou, S; Gonos, ES; Schosserer, M; Grillari, J; Peterson, P; Tuna, BG; Dogan, S; Meyer, A; van Os, R; Trendelenburg, AU

2018

, Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases ,

Ageing Res Rev. 2018; 47:214-277

10.1016/j.arr.2018.07.004

Schosserer, M; Grillari, J; Wolfrum, C; Scheideler, M

2018

, Age-Induced Changes in White, Brite, and Brown Adipose Depots: A Mini-Review ,

Gerontology 2018;64:229–236

10.1159/000485183

Lämmermann, I; Terlecki-Zaniewicz, L; Weinmüllner, R; Schosserer, M; Dellago, H; de Matos Branco, AD; Autheried, D; Sevcnikar, B; Kleissl, L; Berlin, I; Morizot, F; Lejeune, F; Fuzzati, N; Forestier, S; Toribio, A; Tromeur, A; Weinberg, L; Higareda Almara

2018

, Blocking negative effects of senescence in human skin fibroblasts with a plant extract ,

npj Aging and Mechanisms of Diseasevolume 4, Article number: 4 (2018)

10.1038/s41514-018-0023-5

Schosserer, M; Grillari, J

2017

, Biologische Grundlagen des Alterns und dessen Relevanz für die Lebensqualität ,

In: Likar, R; Bernatzky, G; Pinter, G; Pipam, W; Janig, H; Sadjak, A, Lebensqualität im Alter, 3-13; Springer, Berlin, Heidelberg

ISBN 978-3-662-53100-6

Schosserer, M; Grillari, J; Breitenbach, M

2017

, The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy ,

Front Oncol. 2017; 7:278

10.3389/fonc.2017.00278

Garschall, K; Dellago, H; Gáliková, M; Schosserer, M; Flatt, T; Grillari, J

2017

, Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span ,

n p j Aging and Mechanisms of Disease, 3, 5-5

10.1038/s41514-017-0005-z

Markus Schosserer, Beatrix Grubeck-Löbenstein, Johannes Grillari

2015

, Grundlagen der biologischen Alterung ,

Zeitschrift für Gerontologie und Geriatrie

10.1007/s00391-015-0857-4

Schosserer M, Minois N, Angerer TB, Amring M, ... , Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J

2015

, Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan ,

Nature Communications

10.1038/ncomms7158

Dellago, H; Preschitz-Kammerhofer, B; Terlecki-Zaniewicz, L; Schreiner, C; Fortschegger, K; Chang, MW; Hackl, M; Monteforte, R; Kühnel, H; Schosserer, M; Gruber, F; Tschachler, E; Scheideler, M; Grillari-Voglauer, R; Grillari, J; Wieser, M

2013

, High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan ,

Aging Cell. 2013; 12(3):446-458

10.1111/acel.12069

Informationen zur Organisation

Kontakt

Laufende Projekte

Abgeschlossene Projekte

Publikationen

Veranstaltungen